Tumoral calcinosis: a manifestation of extreme metastatic calcification occurring with 1, alpha-hydroxycholecalciferol therapy.
نویسندگان
چکیده
Two cases are reviewed, both of which developed tumoral calcinosis whilst receiving 1, alpha-hydroxy-cholecalciferol therapy. Tumoral calcinosis is an extreme form of peri-articular calcification, and its occurrence in patients with chronic renal failure is unusual. These peri-articular masses developed around the shoulders in both patients, and the action of 1, alpha-hydroxycholecalciferol as a possible factor promoting this form of metastatic calcification is discussed.
منابع مشابه
Tumoral Calcinosis in Chronic Renal Failure : Two Case Reports
Two cases of tumoral calcinosis occurring in patients with chronic renal failure on hemodialysis are described. The aetiology of tumoral calcinosis is described with particular reference to the patients presented. The metastatic calcification occurring in these two cases is most likely related to hyperphosphataemia and secondary hyperparathyroidism possibly aggravated by vitamin D therapy. Trea...
متن کاملSudden onset of parathyroid hormone-independent severe hypercalcemia from reversal of tumoral calcinosis in a dialysis patient
BACKGROUND Tumoral calcinosis is a rare manifestation of extraskeletal calcification, featuring large calcified cystic masses in the periarticular regions of large joints. In chronic kidney disease (CKD), this disorder is thought to evolve through a chronically elevated calcium-phosphorus solubility product leading to calcium precipitation in soft tissue. Treating tumoral calcinosis in these pa...
متن کاملتومورال کلسینوزیس: گزارش موردی
Background: Tumoral calcinosis is a hereditary disorder of metabolic dysfunction of phosphate regulation. It is an idiopathic calcinosis that characterized by the deposition of calcium phosphate in periarticular tissues that causes typically lobulated, well demarcated calcification around large joints particularly the extensor surfaces. It is usually painless. It is common in puberty age and ad...
متن کاملTumoral Calcinosis Causing Bilateral Thigh Pain
We report a case of a 75-year-old female with bilateral thigh pain for several years secondary to soft tissue calcification. Massive calcinosis of the soft tissues is a unique, but not uncommon, radiographic finding. On the contrary, tumoral calcinosis is a rare familial disease. The term tumoral calcinosis has been overly used to describe any massive collection of periarticular calcification. ...
متن کاملRadiology Case Reports
We report a case of a 75-year-old female with bilateral thigh pain for several years secondary to soft tissue calcification. Massive calcinosis of the soft tissues is a unique, but not uncommon, radiographic finding. On the contrary, tumoral calcinosis is a rare familial disease. The term tumoral calcinosis has been overly used to describe any massive collection of periarticular calcification. ...
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 53 623 شماره
صفحات -
تاریخ انتشار 1977